Could 'Supernatural' Season 13 End with Dean Making the Ultimate Sacrifice?

Supernatural has shown a surprising amount of restraint when it comes to killing Sam and Dean. There has been the occasional (very temporary) death of Dean. It's been a while since Supernatural ended a season with one of the brothers dying in a more permanent-ish fashion, which was a staple of the series for a very long time. However, it appears that the closer season 13 gets to its endgame the more likely it is that the old Supernatural trope might return. The episode "Unfinished Business" dropped some heavy hints that Dean could die before the season is out.